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Variolation to Vaccine: Smallpox Inoculation Travels East to West and Back Again

The history of the inoculation process itself might help shed light on the roots of controversies we are facing today. In the spring of 1721, England struggled in the grip of a deadly smallpox epidemic. Mandated shutdowns affected businesses, schools, and social venues, health care services were overwhelmed, and the newspapers reported alarming death tolls. Doctors in London seized the opportunity to introduce the public to the concept of inoculation, which had long been practiced in Asia and th...